The UCD Charles Institute of Dermatology is a facility for research and training in dermatology. It is a national and European centre of excellence. It attracts world leaders in dermatology and will lead to better patient care through the discovery of new treatments and therapies. The new building is also hosting Systems Biology. The institute is combining expertise in systems engineering, mathematical and computational approaches. With state of the art technology platforms. The focus is on biotherapeutics. It will harness the knowledge to develop novel approaches for drug target identification, personalized medicine and toxicity profiles.